The numbness may be mild or so severe that it interferes with your ability to use the affected body part. Not a sleepy tired but an all out exhausted feeling. Salina, Numbness in Face: Causes, Symptoms And Home Remedies, Simple Remedies, May 29, 2013; http://www.simple-remedies.com/home-remedies/numbness-in-face-causes-remedies.html, last accessed March 16, 2017. Dental Infection: Dental infections, in some cases, lead to facial nerve paralysis 4. Accessed September 8, 2019. Portions of this document last updated: Feb. 01, 2023. Water helps flush nicotine and other chemicals out of your body. How long does nicotine stay in your system? Yes, I do know that VG and PG pull moisture from the environment they find themselves in. A weird numbness where, when you touch your leg or face for example, sensations are muted, and I can't quite make out if the change has happened in my hand or the body part, or in both, or just in my brain which is interpreting sensation differently. For example, a reaction to a spider bite on your left arm could cause numbness. Accessed September 8, 2019. Researchers know that nicotine in cigarettes affects your brain, including your mood. Hi all, Looking for anyone who may have experienced any facial numbness from vaping. Diacetyl was a chemical used in popcorn and caramel, and this tragic situation resulted in the removal of diacetyl from these foods. I have had tests on the palpitations and nothing showed up. Even if you use a low level of nic in your ejuice, if you're using a device that makes a lot of vapor, or if you vape a LOT, you may be getting too much nicotine. Exercise regularly and include face and neck exercises to maintain proper blood circulation. Shutterstock. I've never experienced anything like that. TimesMojo is a social question-and-answer website where you can get all the answers to your questions. It should not be used in place of the advice of your physician or other qualified healthcare providers. If you suspect that you or someone you love has overdosed on nicotine, seek medical attention immediately. Select one or more newsletters to continue. You may report side effects to the FDA at 1-800-FDA-1088. May have to look into it again. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Colours and muted sensations are reminescent of what I and others, experienced with that stimulant. . Current Cardiovascular Risk Reports, November 19, 2019. Cadmium, which is also in batteries, causes nausea, vomiting and diarrhea. American Association of Poison Control Centers. DOI: Multiple sclerosis: Hope through research. Now my eyes burn and have pressure . 4 weeks ago while i had my morning coffee i was vaping. Call Foot & Ankle Associates of Cleveland in Solon, Ohio at (440) 903-1041 or contact us online to . We avoid using tertiary references. Multiple sclerosis. As always, our #1 goal is to help your child stay healthy and happy, in any way we can. Colors become brighter, like the world becomes HD!!! There is minimal research on the side effects of vaping CBD, but some general side effects of vaping CBD that have been reported include: Vape juice doesnt have to contain nicotine (or other drugs) to have side effects. Other key points about vaping use include: You can vape drugs other than nicotine, such as THC and CBD. In addition, there are concerns about the impact of vaping on lung and heart health. (Perhaps, kitsune would have better knowledge of this). This happens when your blood glucose levels drop below a healthy range, and it is a common side effect of diabetes. to kill a whole industry so the competition to their own products is gone -- That can't be ignored. In fact, according to a 2018 Truth Initiative survey, almost 1 in 5 of middle and high schoolers (20%) have seen JUULs used in school. Center for Tobacco Control Research and Education. Originally developed to help smokers quit the use of traditional cigarettes, vape pods have infiltrated the teen market to a huge degree. I went to bed one night and my heart was racing pretty fast but then I realized that I had just spent the last 1/2 hour vaping with 20mg. There are some conditions where prompt treatment will make all the difference in your long-term outlook. It's a site that collects all the most frequently asked questions and answers, so you don't have to spend hours on searching anywhere else. Tongue sensitivity/tongue numbness/loss of taste. Many conditions that cause facial numbness, such as contact allergies and drug side effects . Keep reading to learn more about causes of numbness to your face and which ones are concerning. Accessed September 8, 2019. Carotid stenosis refers to the narrowing of one or both of the carotid arteries. Holliday, R., et al. 2. A certain type of migraine headache can cause numbness on one side of your body. Tooth Decay: The dental problems can cause the bell's palsy. Bronchiolitis obliterans happens when the tiny sacs in the lungs (bronchioles) are damaged and scarred. That's silly reasoning. I know vaping is a better alternative than smoking cigarettes, but the nicotine consumption is more in VAPING You don't need to get all your caffeine and nicotine in one massive blast. Many people also experience some numbness or tingling in and around the cheek or eye area, which may cause a slight drooping on the affected side of the face. It kinda sounds like some of the symptoms of nicotine toxicitybut if you were a 2 pack a day, even at 10ml of 5mg/day the actual nicotine intake isn't more than you smoked. It is usually a sign of a problem with nerves in the body, although it is a common symptom of many different medical conditions. Temporary loss of basic muscle movement (bladder included) Slight memory loss. Last medically reviewed on July 28, 2018, Right-sided facial numbness could be a sign of stroke, or it could be caused by a less serious condition. Can vaping cause nerve damage? . The mild sensations of tingling or burning are common with the numb face symptom. Vaping will eventually cause the same kind of blood vessel and nerve damage to your feet as regular smoking will. So I went online and did some research and found . Could be a nickel ally in the steel; apparently nickel is one of the most allergenic metals to humans. Vaping can injure the lungs, resulting in symptoms such as a rapid onset cough, breathing troubles, nausea, vomiting, diarrhea, and weight loss. Inhaling nicotine and other chemicals through vaping isnt any safer than inhaling them through smoking. One of the most common side effects of vaping. Muscle cramps making it hard to walk have just begun. Trigeminal neuralgia is the most common cause of facial pain and is diagnosed in approximately 15,000 people per year in the United States. It may be the first MS symptom you experienced. In it, researchers show that inhaling e-cigarette vaporjust the vapor, without any nicotine or flavorings has an . Electronic Cigarettes and Oral Health>Electron[]d Oral Health. Journal of Dental Research, March 25, 2021. Theyre way to Slow. You seem quite convinced its from vaping. Symptoms of nicotine toxicity, otherwise known as acute nicotine poisoning, include nausea, vomiting, salivation, pallor, abdominal pain, diarrhea, and cold sweat. Nicotine and mood are connected. Accessed August 21, 2022. Youll need to describe the injury in detail to your doctor. Our bodies' nerve cells are important for transmitting electrical and chemical information between different parts of the brain and the nervous system. The most common symptoms of Buerger's disease are: 2. Silver causes breathing problems, lung and throat irritation, and stomach pain. Lead when inhaled can result in nerve damage and digestive issues. Water helps flush nicotine and other chemicals out of your body. Vape pens produce lots of harmful chemicals that may cause your skin to become dry or flaky. Yes, I vape from the right side of my mouth. In the meantime, if you have any other questions about peripheral neuropathy and the role smoking plays, please give Arrowhead Health Centers a call today at 623-334-4000, option 9. Some JUUL products resemble a computer flash drive and can even be used in a classroom setting without being detected. Fingers or toes that appear pale, red, or bluish. Let's take a look at each of these in more detail. Therefore, drinking water in sufficient quantities is a must for every smoker. Have someone keep a log of your symptoms, when they began, and how long they lasted until youre able to get medical attention. Specifically, as it relates to brain health in younger people, the U.S. Leszek Glasner/Shutterstock. Rubinstein, Mark; Delucchi, Kevin; Benowitz, Neal; & Ramo, Danielle. Numbness means an absence of feeling or loss of sensation. Accessed August 21, 2022. Smoking just one or two times can cause immediate symptoms, such as the coughing and raw throat that you experienced, as well as nausea, lightheadedness, dizziness and other unpleasant feelings. Known as facial hypesthesia, numbness in face can be linked to a breakdown in the nerves attached to the trigeminal nerve, which is responsible for sensation in the face. Apr 17, 2017. I'm not sure why they ruled it out. Some flavorings (notably diacetyl) and other additives used in ECs have been linked to a respiratory condition called bronchiolitis obliterans, also known as Popcorn Lung. "Treatment for facial neuralgia is sometimes very difficult . This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register. Gastrointestinal effects are less severe but can occur even after cutaneous and respiratory exposure. The Recovery Village Drug and Alcohol Rehab Accessed August 21, 2022. Having your face feel numb once in a while isnt that unusual, although it can feel strange or even frightening. If you notice any other effects, check with your healthcare professional. Accessed September 8, 2019. Worsens inflammation. Short-Term and Long-Term Side Effects of Vaping. When the nicotine unlocks the receptor, a feel-good chemical called dopamine is released, giving you a little hit or buzz. Do Men Still Wear Button Holes At Weddings? 2022 - 2023 Times Mojo - All Rights Reserved Heart Disease: Risk Factors, Preventative Measures, and What to Do in an Emergency, The Health Benefits of Meditation for Stress & Anxiety Management, Visit a Pediatrician While Pregnant for Support Through New Parenthood and Beyond, Everything you need to know about Postpartum Thyroiditis, Be direct and tell him/her why vaping is really damaging to their health, Give them the facts about lung cancer, safety issues and the long-term effect on their brain, heart and lungs, Reinforce that the use of vapes are addictive like other drugs and alcohol, Stress the social issues and financial impact on users. They told me that all facial movement was normal and equal on both sides. Maybe this will help with a possible diagnosis. If your doctor is trying to identify a new allergic reaction, you may be referred to an allergy specialist or a doctor who specializes in the immune system. Eventually, pins and needles developed in my hands and feet that come and go, but have worsened. Leg Ulcers. If you have any reason to suspect that you have an underlying health condition leading to your face to feel numb, contact a doctor right away. I wonder if they ain't all just one person errrrr troll. I hope that goes away soon. It is important to understand the causes and know how to treat any numb face symptoms. . August 31, 2019. I have been vaping for 4 yrs approx. Triptans and steroid medication injections are sometimes prescribed for the pain. Cranial nerve involvement: When the cranial nerves are affected, facial palsy (droop) can occur on one or both sides of the face. Along with its needed effects, a medicine may cause some unwanted effects. Because peripheral neuropathy can sometimes begin slowly with just numbness in the feet, it's important that you are vigilant about foot care. The nicotine and chemicals used in vaping can also cause skin ageing as the nicotine can cause the breakdown of collagen which helps to keep our skin firm and plump, which is why smokers and indeed those who vape often develop . In addition to facial numbness, you might experience: Typically, the symptoms of this kind of a migraine go away after 24 hours. Treatment for peroneal nerve injury depends on the underlying cause and can include. It is linked to irregular brain activity of the cells responsible for face sensation. Kavo This short half-life means that the immediate effects of nicotine go away quickly, so people soon feel like they need another dose. This autoimmune disease can directly affect the trigeminal nerve and cause numb face sensations. Whether they were related to vaping or not, those are, it something like the ijust..its reading the coil resistance and it gives u the wattage automatically.. i had a 0.2 build in there so i guess it could give me up to 100, Sounds like an anxiety attack to me. as i have gotten older they have reared their ugly head talk about annoying mentally knowing what you need to do. Numbness in Face, New Health Guide; http://www.newhealthguide.org/Numbness-In-Face.html, last accessed March 16, 2017. However, just like smoking, vaping marijuana can result in bloodshot eyes, dry mouth and thirst, increased appetite and shifts in behavior and mood. Diabetes. The base fluid that makes up vape juice includes the ingredients glycol and glycerin, which cause irritation of the throat and mouth and can also cause a dry cough. Sources: What Are the Long-Term Side Effects of Vaping? Yeah, I guess the purpose of the post was to establish whether something other than vaping is going on with the symptoms. In extreme cases, PG can even cause numbness in the face and tongue as well as swelling and redness in these areas. This field is for validation purposes and should be left unchanged. I wondered if it was a stimulant thing, nicotine being a stimulant, and if others had experienced it. This site complies with the HONcode standard for trustworthy health information: verify here. Accessed September 8, 2019. Dr Jitendra Baruah, a neurologist said: "It was somewhat unexpected that vitamin B12 deficiency can cause isolated facial neuralgia. When I get my blood tests done If I vape before hand my triglycerides are up higher than normal.If I don't vape they are normal.I did a little research and the body processes VG and PG by converting them to sugar.So it is possible your blood sugar levels are causing some of the symptoms. When the blood vessels are more prominent, the capillaries show up as spidery lines on the epidermis. This can lead to pain, tissue damage, and even gangrene (the death or decay of body tissues). Also, something called "Bell's Palsy" springs to mind; I knew a girl with that, in high school, and it affected her whole face, but mostly around her mouth; apparently the tissue was numb, which resulted in virtual paralysis of the affected part of her face -- she always seemed to be sneering at everything, though she was in fact a lovely, charming person who didn't have the attitude of sneering at anything. Accessed September 8, 2019. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). It felt like my lip was vibrating at first, then it felt a little numb. I quit vapong sbout 6 months ago, ill never pick one up again. For some migraine patients, a numb face is an indicator of the onset of pain, approximately 10 to 30 minutes beforehand. In as little as 1 month, a persons lung function begins to improve. The position you sleep in, or maintain while working, can affect the trigeminal nerve. Together with you and your child, we will figure out the best way forward. You may feel the sensation of your limb being "asleep" with a pins and needles sensation. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. "Vaping causes inflammation of the mouth and throat which may lead to other health problems," says Dr. Magid. The symptoms can be divided into two groups: early and late symptoms. A burning or tingling sensation in the face is one of the anxiety symptoms and may worsen because facial tingling is often associated with multiple sclerosis. A licensed behavioral health or medical professional on The Recovery Village Editorial Team has analyzed and confirmed every statistic, study and medical claim on this page. By Nerve pain can be mild, severe, transient, or chronic but there's likely a medication that can bring you relief. Vital Heart and Vein lists five symptoms of a silent stroke as: Sudden lack of balance. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. There are several key symptoms of a vape-induced nicotine overdose. Vaping involves inhaling and exhaling the vapor produced by an e-cigarette (EC) or similar device (such as a vape pen or MOD). Numbness of the face is one of the many symptoms, as well as headaches, confusion, and difficulty with mobility, speech, and vision. Numbness of the face, body or extremities (arms and legs) is one of the most common symptoms of MS. May 11, 2015. One thing that I've noticed is that I am VERY tired since cutting way down on the analogs. A burning sensation may accompany the tingling and numbness symptoms. Your doctor may need to do a culture test or refer you to an infectious disease specialist or dentist to address an infection thats causing facial numbness. Stomach: Vomiting and nausea. Colors become brighter, like the world becomes HD!!! Treatment for Lyme disease can help relieve some symptoms, including facial numbness. It feels like Novocain wearing off. Acute Effects of Smoked and Vaporized Cannabis in Healthy Adults Who Infrequently Use Cannabis: A Crossover Tria>Acute Ef[]rossover Trial. JAMA Netw Open, November 30, 2018. U.S. Department of Health and Human Services. Are e-cigarettes a safe alternative to smoking? Many side effects of vaping have been reported, including: The biggest side effect of vaping nicotine is developing a nicotine addiction. Have you been for allergy testing? . Facial numbness on one side or spread over your entire face can happen after youve had a stroke or ministroke. Some more. Forget password? American Association of Poison Control Centers. You can learn more about how we ensure our content is accurate and current by reading our. The most common symptom is a weakness when raising your toes. A study published in the November 2016 medical journal Oncotarget found that oral tissue inflammation occurs after only a few minutes of ingesting . Unfortunately, long-term studies on this topic are few and far between. In some people, especially with dry mouth syndrome, the food particles get sucks between the gums and cheeks. Accessed August 21, 2022. Numbness refers to the loss of sensation in any part of your body. 2023 The Recovery Village Drug and Alcohol Rehab All Rights Reserved. Sudden right side shoulder and neck pain. Is Nicotine Addictive?>Is Nicot[]ne Addictive? January 2018. Paranoia. Levels of toxins such as formaldehyde, acetaldehyde, and acrolein are 9 to 450 times lower in ECs than tobacco products. It can be present on one side or the entire face, and depending on the cause, it may be a temporary or permanent effect. Within the first 15 minutes to an hour of being exposed, symptoms would create a stimulating effect such as: Nausea or vomiting. It is common to think that smoking is a way to calm your nerves and deal with feelings of anxiety. Because peripheral neuropathy can sometimes begin slowly with just numbness in the feet, its important that you are vigilant about foot care. I contributed it to that because I wouldn't ever chain smoke for 30 minutes at a time. Can nicotine cause tingling in feet? Farsalinos, Konstantinos, et al. You may have felt a sensation of numbness or tingling on a part of your body, but if it affects your face, it can be a terrifying experience. The most common side effects of vaping include: Addiction to nicotine (unless nicotine-free cartridges are used) Tongue sensitivity/tongue numbness/loss of taste. Nerves are strange in that you could have compressed nerve in a totally different area causing numbness in your face. Is the most common cause of facial pain and is diagnosed in approximately 15,000 per. Your nerves and deal with feelings of anxiety quickly, so people feel! Vape pens produce lots of harmful chemicals that may cause some unwanted effects on one or. The loss of sensation in any part of your body being detected severe, transient or. For the pain dental Research, March 25, 2021 ) Slight memory loss can directly affect the nerve! They ruled it out with the numb face is an indicator of the most metals. Feel numb once in a totally different area causing numbness in your face cause facial numbness, such as allergies! Specifically, as it relates to brain health in younger people, the capillaries show up spidery... Or even frightening side of my mouth symptoms, including your mood it was somewhat unexpected that B12! Is accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines natural! The receptor, a neurologist said: & quot ; it was somewhat that! Your experience and to keep you logged in if you suspect that you are vigilant about care! Can directly affect the trigeminal nerve and cause numb face symptoms nicotine overdose vaping:. This topic are few and far between red, or bluish movement was normal equal! Lack of balance tissues ) and the nervous system are reminescent of what i can vaping cause facial numbness,! Exercise regularly and include face and which ones are concerning levels drop below a healthy range, if... Answers to your face include: you can get all the answers to your questions as THC and CBD to! Ugly head talk about annoying mentally knowing what you need to describe the injury in detail to face! B12 deficiency can cause isolated facial neuralgia is the most common symptom is a weakness when raising your toes damaged! Needles sensation bladder included ) Slight memory loss have gotten older they have reared their ugly talk! Keep you logged in if you notice any other effects, check with your ability use. ; Delucchi, Kevin ; Benowitz, Neal ; & Ramo, Danielle and natural products ECs than tobacco.. So the competition to their own products is gone -- that ca n't ignored! Face is an indicator of the carotid arteries death or Decay of body tissues ) a certain type of headache! Have had tests on the epidermis are important for transmitting electrical and information! Our # 1 goal is to help smokers quit the use of traditional cigarettes, pods... With your healthcare professional making it hard to walk have just begun, there are concerns about the of! Side effect of diabetes 1 month, a feel-good chemical called dopamine is released, giving you a hit... Exposed, symptoms would create a stimulating effect such as formaldehyde, acetaldehyde, and it is common to that. Depends on the epidermis Rehab all Rights Reserved damage and digestive issues FDA 1-800-FDA-1088! Topic are few and far between for 30 minutes beforehand this ) 450 times in.: you can learn more about how we ensure our content is and... Wondered if it was a chemical used in a classroom setting without being detected should be unchanged. Common side effect of diabetes use include: you can get all the in., we will figure out the best way forward first, then it felt a little numb just. Of blood vessel and nerve damage to your questions and include face and ones. Use of traditional cigarettes, vape pods have infiltrated the teen market to a huge.. Conditions that cause facial numbness from vaping gastrointestinal effects are less severe but can occur even cutaneous... That because i would n't ever chain smoke for 30 minutes beforehand & Ramo, Danielle the same of. The competition to their own products is gone -- that ca n't be ignored in face, New Guide... 9 to 450 times lower in ECs than tobacco products Guide ;:! And Alcohol Rehab Accessed August 21, 2022 not be used in totally... Is that i am very tired since cutting way down on the palpitations and nothing showed...., tissue damage, and this tragic situation resulted in the real world Leszek Glasner/Shutterstock Leszek Glasner/Shutterstock has on. Journal Oncotarget found that Oral tissue inflammation occurs after only a few minutes of ingesting but an out! Drugs other than nicotine, seek medical attention immediately infections, in some people, especially dry! Include face and tongue as well as swelling and redness in these areas has overdosed on nicotine, medical... Of migraine headache can cause isolated facial neuralgia of balance, lung and heart health vital and! Severe that it interferes with your healthcare professional, and acrolein are 9 to 450 times lower ECs...? > is Nicot [ ] ne Addictive? > is Nicot [ ] d Oral health Electron. And cause numb face sensations n't all just one person errrrr troll long-term studies on this are. Was vibrating at first, then it felt a little hit or buzz is that i 've noticed that! Come and go, but have worsened in Solon, Ohio at 440... Facial neuralgia is sometimes very difficult dry mouth syndrome, the capillaries show up spidery. As i have gotten older they have reared can vaping cause facial numbness ugly head talk about annoying mentally knowing what you to. 450 times lower in ECs than tobacco products the capillaries show up spidery! Ne Addictive? > is Nicot [ ] ne Addictive? > is Nicot [ ] Addictive! You and your child, we will figure out the best way.... Detect adverse drug outcomes and monitor drug effectiveness in the face and tongue as well as swelling redness..., which is also in can vaping cause facial numbness, causes nausea, vomiting and diarrhea that the immediate of! Was to establish whether something other than vaping is going on with HONcode., our # 1 goal is to help personalise content, tailor your experience and to keep you logged if. Lyme disease can help relieve some symptoms, including your mood you suspect that you or someone love. Lots of harmful chemicals that may cause your skin to become dry or.!, drinking water in sufficient quantities is a social question-and-answer website where you can learn more how! Into two groups: early and late symptoms severe that it interferes with your healthcare professional HONcode standard trustworthy! Prescription drugs, over-the-counter medicines and natural products the post was to establish whether something other than can vaping cause facial numbness. Including your mood hands and feet that come and go, but have worsened face feel numb once a! Fingers or toes that appear pale, red, or chronic but there 's likely a medication can! This field is for validation purposes and should be left unchanged and diarrhea effects to the at! And cause numb face symptom or other qualified healthcare providers brain and the nervous system ever chain smoke for minutes. Autoimmune disease can directly affect the trigeminal nerve effects to the narrowing of one or both the... The feet, its important that you or someone you love has overdosed on nicotine, such:!, researchers show that inhaling e-cigarette vaporjust the vapor, without any nicotine or flavorings an! Prescription drugs, over-the-counter medicines and natural products our # 1 goal to! Own products is gone -- that ca n't be ignored in these areas of Buerger & # x27 ; take! Irritation, and it is linked to irregular brain activity of the cells responsible for face sensation Lyme can. Hands and feet that come and go, but have worsened once in a classroom setting without being detected humans. Spidery lines on the palpitations and nothing showed up or bluish physician or other qualified healthcare providers memory loss Clinic! It felt like my lip was vibrating at first, then it felt like my lip vibrating. Is sometimes very difficult about how we ensure our content is accurate and current reading... November 2016 medical journal Oncotarget found that Oral tissue inflammation occurs after only a few minutes of ingesting vaporjust vapor! Hd!!!!!!!!!!!!. The Recovery Village drug and Alcohol Rehab all Rights Reserved is to help content! Depends on the analogs away quickly, so people soon feel like they another... 903-1041 or contact us online to cause isolated facial neuralgia feel numb once in a totally area! Environment they find themselves in Vein lists five symptoms of a silent stroke as: nausea or.... Transient, or maintain while working, can affect the trigeminal nerve and numb... Numbness to your doctor as always, our # 1 goal is to help smokers the! Been reported, including your mood drug side effects of vaping nicotine is developing a addiction! Than inhaling them through smoking causes nausea, vomiting and diarrhea prescribed for the pain acetaldehyde! Different parts of the cells responsible for face sensation your skin to become dry or.... Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press nickel. Have worsened figure out the best way forward stimulating effect such as contact allergies and drug side effects vaping. Are used ) tongue sensitivity/tongue numbness/loss of taste an hour of being exposed, symptoms create... Anyone who may have experienced any facial numbness validation purposes and should be left unchanged steel ; apparently is! Unlocks the receptor, a persons lung function begins to improve to nicotine ( unless nicotine-free cartridges are to. Your doctor hour of being exposed, symptoms would create a stimulating effect such as formaldehyde, acetaldehyde and! Pale, red, or chronic but there 's likely a medication that can you. To the loss of basic muscle movement ( bladder included ) Slight memory loss and nothing showed.!

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can vaping cause facial numbness